Increased risk of hypotension with high doses of diuretics (e.g. furosemide, hydrochlorothiazide) and other antihypertensives. May elevate plasma concentrations of digoxin. Increased risk of hyperkalaemia with K-sparing diuretics (e.g. spironolactone, eplerenone, triamterene, amiloride), K supplements or K-containing salt substitutes; ACE inhibitors, heparin, immunosuppressants (e.g. ciclosporin, tacrolimus), trimethoprim. May reduce antihypertensive effect and deteriorate renal function with aspirin, NSAIDs including selective COX-2 inhibitors. May increase serum lithium levels and toxicity. Decreased antihypertensive effect with systemic corticosteroids. Potentially Fatal: Dual blockade of the renin-angiotensin-aldosterone system (RAAS) by concomitant use with ACE inhibitors or aliskiren may cause an increased risk of hypotension, hyperkalaemia and impaired renal function (esp in patient with diabetes mellitus or renal impairment).
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Jubitel (Telmisartan Tablets 40mg)
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